Therapeutic and toxic effects observed with different dosage programs of cyclophosphamide in treatment of steroid-responsive but frequently relapsing nephrotic syndrome

McCrory WW, Shibuya M, Lu WH, and Lewy JE

Journal of Pediatrics. 1973; 82(4): 614-618.

Cyclophosphamide [Therapeutic Use] [Administration & Dosage] [Adverse Effects]; Nephrotic Syndrome [Drug Therapy]; Prednisolone [Therapeutic Use] [Administration & Dosage]; Adolescence; Alopecia [Chemically Induced]; Child; Child,Preschool; Dose-Response Relationship,Drug; Drug Synergism; Gastrointestinal System [Drug Effects]; Leukopenia [Chemically Induced]; Lymphopenia [Chemically Induced]; Proteinuria [Drug Therapy]; Recurrence; Remission,Spontaneous; Urogenital System [Drug Effects]

RCT